Sentence examples for be of pathogenic importance from inspiring English sources

They prolong xenograft survival and it should be noted that C1q is activated by several substances which may be of pathogenic importance but only by antibodies [52].

The typical cellular pattern in the synovium of the RA-joint with its abundance of highly differentiated cells implies the possibility that Flt3-L, with its ability to induce differentiation and proliferation, could be of pathogenic importance.

Farber et al. [ 8] suggested that neuropeptides presented in unmyelinated dermal nerve endings may be of pathogenic importance in psoriasis.

YKL-40 seems to be of pathogenic importance in the low-grade inflammation that precedes the development of CVD.

Despite less striking differences in the proportions of memory and/or naïve B and CD4+ T cells, these changes may also be of pathogenic importance.

An unbalanced relationship between expression of IL-1β and its antagonist IL-1ra could be an indicator for an imbalance between pro-inflammatory and modulating cytokines, which has been demonstrated to be of pathogenic importance in chronic inflammatory diseases [ 47].

Low grade inflammation is of pathogenic importance in atherosclerosis and in the development of cardiovascular disease (CVD) and type 2 diabetes (T2D).

Nevertheless, this suggests that underexpression of MAP9 might be of pathogenic and prognostic importance, so that this protein might have potential as a new tumor marker for colorectal cancers even though its expression does not correlate with tumor progression and as a drug target for development of new therapies.

Among gastro-intestinal nematodes, the blood-sucking worms belonging to the subfamily of Haemonchinae are considered to be of pathogenic and economic great importance, particularly in small ruminants.

Studies on their molecular identification, antifungal susceptibility, and comparisons with the clinical outcomes would be of great importance, as the pathogenic potential may vary between these genera.

In the context of CHB, these limitations are all the more relevant considering that induction of disease depends on the antibody response elicited in the mother and that maternal major histocompatibility complex (MHC) has been shown to be of importance in the generation of pathogenic antibodies in CHB [ 55].