Sentence examples for be of pathogenetic importance from inspiring English sources

The majority are CD4+, although CD8+ T cells are also present and may be of pathogenetic importance [78].

A Th1/Th2 cytokine imbalance with a predominance of Th1 cytokines, including IFN-γ, is suggested to be of pathogenetic importance in RA [ 12- 14].

The circulating levels of anti-dsDNA often correlate with disease activity, and these autoantibodies are presumed to be of pathogenetic importance in lupus nephritis [ 4- 6].

A Th1/Th2 cytokine imbalance with a predominance of Th1 cytokines, including IFN-γ, is suggested to be of pathogenetic importance in RA [ 13- 15].

Recent data suggested an increased frequency of KIT aberrations in mucosal melanomas, whereas c-KIT in most types of cutaneous melanomas does not appear to be of pathogenetic importance.

A Th1/Th2 cytokine imbalance with a predominance of Th1 cytokines, including IFN-γ, is suggested to be of pathogenetic importance in autoimmune diseases, such as rheumatoid arthritis and SLE [ 11- 13], while predominance of Th2 cytokines, including IL-4, is important in allergic reactions, such as bronchial asthma [ 14].

Diagnosis of infectious arthritis based on the specific detection of nucleic acids is also an option, even though results should be interpreted cautiously, as they are not always of pathogenetic importance [ 37].

1 Insulin resistance has been proposed to be of key pathogenetic importance.

While overexpression is not as strong evidence of pathogenetic importance, it can be an important oncogenic mechanism in some instances.

Obesity is of major pathogenetic importance to type 2 diabetes, it contributes to poor glycemic control and increases the risk of cardiovascular disease.

Employee health shall be of extreme importance.