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Studies with between nine and 11 positive scores were considered to be of high methodological quality, those with between five and eight positive scores to be of moderate quality and those with less than five positive scores to be of low methodological quality.
A larger, systematic review that we have carried out this year (manuscript submitted for publication), with the inclusion of new studies performed to date, and with the incorporation of those published in Chinese in the last 10 years, shows that studies contain to be of low methodological quality.
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The majority of studies were of low methodological quality with only little overlap in methodology and cytokines investigated.
Since a part of the selected studies were of low methodological quality (<10 points), the reported morbidity rates might dissent from well-designed studies, powered on morbidity.
All were of low methodological quality.
These results show that the majority of the studies were of low methodological quality.
Many of the included studies were of low methodological quality and participant numbers were small.
The studies were of low methodological quality and reported dissimilar outcomes precluding any formal synthesis.
All studies were of low methodological quality (Jadad score ≤2; possible range 0 5).
However, the evidence is inconclusive because clinical trials included in the two systematic reviews were of low methodological quality.
The included primary studies are of low methodological quality; the RCTs lack any information about randomisation, allocation concealment and blinding.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com