Results: We identified 945 people with >1 occurrence of TBI; 35% were of higher severity than the preceding ones.
Thus, most studies concluded that concomitant injuries had either no effect on outcomes, or had effects only if the injuries were of high severity.
In their update of the Beers' criteria, Fick et al. designated flurazepam, amitriptyline, chlordiazepoxide, doxepin, and anything other than low doses of short-acting benzodiazepines (e.g., >3 mg lorazepam) as potentially inappropriate for use in older patients; adverse outcomes for all such medications were deemed by the authors to be of high (versus low) severity [ 14].
Local reactions were significantly more likely in the 80 µg AMA1+CPG group versus the 80 µg AMA1 group (OR 14.50, 95% CI 1.72 122.40, p = 0.0140), and reactions were more likely to be of a higher severity (moderate or severe versus mild or none) (OR 15.54, 95% CI 3.81 63.36, p = 0.0001).
"We are going to see more fires, over larger areas, that are more frequent and of higher severity.
In the final adjusted model, influenza infection was the strongest independent predictor of higher severity score, with a mean increase of 1.7 points compared to those who were influenza negative (p < 0.001).
But in the case of a patient who is going downhill, if I could intervene to stop that process in any way it would, of course, be a condition of high severity".
First, participants were of high heterogeneity, regarding severity or activity of disease, menopausal status, or treatment, which decreased the generalizability of our results.
Additionally, the amount of root shortening 6 to 12 months after bracket placement is of high predictive value for the severity of root resorption after the completion of treatment [2].
It is therefore a lesson for future diarrhoeal epidemic situations that initial triage and assessment of dehydration severity is of high importance, and impacts both on individual patient treatment, and on managing finite resources.
