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Future economic evaluations of DM programs should target a wider population of COPD-patients and be of higher methodological quality.
On the other hand, future studies need to be of higher methodological quality and particularly use validated tools.
There are currently more than 3,000 Cochrane reviews and they have been shown to be of higher methodological quality, on average, than other systematic reviews [ 14, 15].
These databases are sources of systematic reviews that tend to be of higher methodological quality, which may reflect better reporting and hence better indexing.
Given the evidence that Cochrane reviews tend to be of higher methodological quality compared with other reviews, 7 8 our secondary objective was to investigate differences in findings between Cochrane and non-Cochrane reviews.
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These studies are designed to rigorously synthesize scientific literature; however, cannot be assumed to be of high methodological quality.
†Trials considered to be of high methodological quality.
In general, trials were considered to be of high methodological quality.
1 5 12 20 23 25 Overall, we considered five trials to be of high methodological quality, 1 5 12 20 23 with a low risk of bias.
Five trials were considered to be of high methodological quality (low risk of bias), whereas the rest were low quality (high or unclear risk of bias).
The authors judged nine studies to be of high methodological quality, four studies to be high/moderate quality, with the remaining 17 studies being of lower quality.
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