Your English writing platform
Discover LudwigSuggestions(5)
Exact(1)
Cross-reactive clones tend to be of higher avidity with greater cytokine production than serotype specific clones.
Similar(59)
In addition, the antibodies generated were of higher avidity.
Dengue cross-reactive CTL clones derived from these patients were of higher avidity than serotype-specific clones and produced much higher levels of both type 1 and certain type 2 cytokines, many previously implicated in dengue pathogenesis.
This suggests that one of the bands may be a ligand of higher avidity while the second one is of lower avidity.
However, more recently we found that T-cell responses were more robust after vaccination with the natural peptide, since the T cells were more strongly activated and were of higher functional avidity as compared with T cells after vaccination with the analog peptide 39.
The T cell responses we detected to the CAPAGFAIL epitope were also of high avidity, so may have been better-able to cross-recognise our test peptide in spite of sequence differences to the autologous virus sequence than lower avidity responses to other viral epitopes.
Abnormal memory effector cells in SLE have specificity for autoantigen with surface immunoglobulin that is usually of high avidity because of somatic hypermutation of immunoglobulin variable regions and possible switching to the IgG isotype.
We have previously reported the novel finding that intranasal infection with the paramyxovirus SV5 induces a CD8+ T cell response to the SV5 P protein that is almost exclusively of high avidity.
The most important correlate of vaccine-induced protection from measles is the presence of high avidity neutralizing antibody at the time of exposure to wild type MV [37].
Further studies are needed to investigate whether ACPA-IgG autoantibodies of high avidity are indeed produced by bone marrow derived plasma cells or whether other mechanisms are responsible for the differences in avidity of ACPA autoantibodies, for instance consumption of high avidity ACPA-IgG autoantibodies at sites of synovial inflammation.
In order to determine if CD25+ Tregs may be preventing or regulating the development of high avidity memory immunity, anti-CD25 monoclonal antibodies were used to deplete Tregs prior to immunization.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com