Sentence examples for be of high affinity from inspiring English sources

Based on the fold changes of iolA (cre-1) and iolB (cre-2), both cre-1 and cre-2 seem to be of high affinity.

Aβ binding to PrPC has consistently been shown to be of high affinity and is exquisitely specific for the oligomeric form, with little or no affinity for fibrillary or monomeric Aβ peptide [ 1, 35- 37].

These findings emphasize that, although peptides with binding scores greater than 2 may be of high affinity, other sequences falling below this range (>0) can elicit an immune response.

Either model would predict that on a non-transgenic background, the affinity of the TCRs expressed by Itk null CD4+ T cells would tend to be of higher affinity so as to overcome the reduction in TCR signals in the absence of Itk.

Antibodies were of high affinity and capable of neutralising the bioactivity of hCG but were devoid of anti-peptide reactivity.

While the binding of the IFNAR2 receptor to interferon is of high affinity and well characterized, the binding to IFNAR1 is weak, transient, and poorly understood.

In the present study, a novel nano-platform (AuNC-cRGD-Apt) with dual targeting function was initially established by conjugating gold nanocluster (AuNC) with cyclic RGD (cRGD) that is specific to αvβ3integrins over-expressed on the surface of tumor tissues and aptamer AS1411 (Apt) that is of high affinity to nucleolin over-expressed in the cytoplasm and nucleus of tumor cells.

For two peptides, [Lys102]CFTR(102-116) and CFTR(1468-1480), antibody-peptide binding was of high affinity in that half-maximal binding occurred at peptide concentrations below 10 nM.

Binding was optimal at physiological values for ionic strength and pH, was of high affinity (Kd = 20-60 nM), and the capacity of 25 pmol/mg of brain membrane protein is in the same range as the number of spectrin tetramers (30 pmol/mg).

Both populations of antibodies were of high affinity (>1010 l/mol).

EBER-1 was chosen as the target RNA for this assay as its interaction with L22 has been well characterized and is of high affinity [19], [25] [27].