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The scale of these differences and preliminary GO analysis indicate a persistent signature of the TSGD event that may be of functional significant for the subsequent evolution/diversification of each lineage.
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This and other polymorphisms if proven to be of functional significance could represent potentially significant candidate genes in the regulation of tumour angiogenesis.
An estimate of the rate of functional significant stenosis is given by the rate of interventions multiplied by a factor of 0.63 which is the fraction of functionally significant stenosis in the FAME trial [ 23].
In spite of the great structural similarity revealed for the TM domains of LeuT and the eukaryotic NSS, it is clear that the long N- and C-terminal regions found only in the eukaryotic transporters but not in LeuT, represent a major difference that is likely to be of significant functional importance.
However, Kourtzis et al. [13] suggested that the low demands of the elderly permit this degree of shortening to be of no significant functional compromise.
The direct repeats may have a recent evolutionary origin, frequently conduct copy corrections, and are of significant functional relevance.
We anticipate that the availability of these sequences will be of significant value to functional studies in C. hominivorax and closely related species in the Calliphoridae family.
This tool promises to be of significant utility for high throughput functional genomics studies in Z. tritici.
Few such studies have focused on porous anodic oxides, which are of significant interest as functional materials.
Acetylcholine is a central nervous system neuromodulator that is of significant behavioral and functional importance.
Heterogeneities in structure and stress within heart valve leaflets are of significant concern to their functional physiology, as they affect how the tissue constituents remodel in response to pathological and non-pathological (e.g. exercise, pregnancy) alterations in cardiac function.
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