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The results show that backbone-correlated motions are a fundamental property of β-sheets and that they can be of functional relevance.
This convergent event, which we describe here for the domain combinations, might be of functional relevance.
The conservation of this site during the evolution suggests that this target may be of functional relevance.
This possibility of inducing strand separation due to formation of a G4 DNA could be of functional relevance in processes other than transcription.
In addition, integrin signaling has been shown to be of functional relevance for both neural crest [20] and mesenchymal development [21], [22].
The cardiac expression of FMR4 may possibly be of functional relevance considering the fact that many patients with fragile X syndrome exhibit heart defects such as dilation of the aortic root and mitral valve prolapse [24], [28].
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The first PCA components describe the large-scale collective motions of a structure, which are of functional relevance and are also similar to the normal modes from ENMs.
Furthermore, analysis of amino acid variability between different human eIF5A isoforms revealed peculiar structural characteristics that are of functional relevance.
The effects of p21 were of functional relevance because knockdown of p21 promoted anti-T.
The FASTSNP programme (http://fastsnp.ibms.sinica.edu.tw/pages/input_CandidateGeneSearch.jsp) was employed to establish whether SNPs were of functional relevance [35].
We combined bioinformatic and experimental approaches to identify motifs within the FSCN1 promoter that are of functional relevance to the pathological expression of fascin in human carcinomas.
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be of operational relevance
be of limited relevance
be of prognostic relevance
be of particular relevance
be of pathophysiological relevance
be of clinical relevance
be of significant relevance
be of major relevance
be of high relevance
be of physiological relevance
be of therapeutic relevance
be of biological relevance
be of general relevance
be of potential relevance
be of special relevance
be of minor relevance
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