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The ATPase and 5' phosphatase function of NSs could also be of functional importance in the replication and transcription of the virus.
There were also 11 additional SNP hotspots, some of which might be of functional importance.
The most central ones are presumed to be of functional importance for the specific network.
One of these water molecules, WAT1, which is within hydrogen bonding distance from the oxygens of both catalytic aspartates, may be of functional importance.
We wondered whether the presence of a leucine instead of the conserved residue Phe217 of the APH1B protein would be of functional importance.
In SPMS patients without prior ON RNFL thinning might also be of functional importance since VEP were found pathologic in 83%, high-contrast visual acuity (EDTRS) in 50% and colour vision testing in 33% of 12 investigated eyes.
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Namekawa and colleagues [ 54] demonstrated the presence of these cells in the synovial tissue of patients with RA, again postulating that the gain in cytotoxic function is of functional importance in maintaining chronic synovitis.
The set of residues near ligands and catalytic sites includes many sites that are not important for specificity for example, sites that are of functional importance to the whole family and thus are conserved across the specificity groups.
These data suggest that parkin is of functional importance for selective loss of dopamingeric neurons and the onset of PD in aged mice.
Since earthworms are of functional importance in soils, understanding their sensitivity to tillage is of importance for the design of sustainable management systems.
Pol3 interacts with Pol31 thanks to its C-terminal domain (CTD) and this interaction is of functional importance both in DNA replication and DNA repair.
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Justyna Jupowicz-Kozak
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