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Detailed information about interruptions, their source and nature are needed, and interruptions and MAEs should be obtained using validated direct observational methods.
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Several typical stack configurations are considered and the flow field in the stacks is obtained using validated computational fluid dynamics (CFD) modelling with OpenFoam software.
Information about smoking habits and physical activity was obtained using validated questionnaires.
However, outcomes are obtained using validated patient self-report measures, and analysis will be performed blind to treatment allocation.
Surgeon opinion was obtained using validated questionnaires at a Specialist Hip Meeting (n = 61, 30 of whom stated that they routinely performed FAI surgery) and patient opinion was obtained from clinical patients with a new diagnosis of FAI (n = 31).
Further, a second relevant result is obtained using the validated method to perform an optimization of the geometry of the joints for a safer design.
After obtaining demographic data and information on the general health status from each participant, information of medication adherence was obtained using the validated Morisky Adherence Scale-8 (MMAS-8).
The subsequent development of diabetes and hypertension were obtained using the validated Ontario Diabetes and Ontario Hypertension Databases [ 23, 24].
History of diseases such as diabetes, cancer, cardiovascular disease and high blood pressure was also collected.Information on physical activity was obtained using a validated questionnaire [ 9].
Quantitative cartilage measurements of normal and OA subjects' knees were obtained using a validated segmentation technique on both 1 T and 1.5 T MRI images.
Concentrations of E7820 in plasma were obtained using a validated liquid chromatography method with UV detection, with precision <15% over the entire concentration range.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com