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The cost of implementing the exercise and home hazard program will be obtained from trial records and NeuRA financial records.
Information on the other healthcare consumption will be obtained from trial participants by means of a cost questionnaire, which was developed for this purpose and incorporated into the case report files of the MIND-DIA trial.
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Additional information was obtained from trial authors.
Information regarding the quality of the three unpublished studies was obtained from trial protocols and personal communication with the trialists.
A quarter of all clinical data submitted to European drug regulators to secure market approval for a new drug has been obtained from trials in low- and middle-income countries.
The training task results are obtained from trials of each supervised learning algorithm applied to 294 annotated posts per trial.
Data on lenalidomide, bortezomib and 90yttrium-ibrutumomab tiuxetan are obtained from trials specifically designed for patients affected by marginal zone lymphoma and with various disease presentations.
Importantly, several of these recommendations were derived from clinical trial data that have been obtained from trials with specific entry criteria.
These meta-analytical findings should be considered with caution because they were obtained from trials designed for other purposes (usually efficacy on glucose control) without any clear definition of methods for screening and criteria for diagnosis of cardiovascular events.
Data necessary for meta-analyses could not be obtained from 14 trials, so we initially included 43 trials [ 7- 49] (Fig. 2).
Thus, more information will have to be obtained from further trials or soon become available from registries.
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