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If this anti-tumorigenic effect will also be observed in clinical trials, which are currently pursued, remains to be seen (https://clinicaltrials.gov/) [ 45].

Due to the high linkage disequilibrium in the MHC region, only a limited set of DQA1*-DQB1* haplotypes (DQ types) are observed in the general population (see http://depts.washington.edu/rhwlab/resMat/dq/linkage.html for an example of common combinations of DQA1* and DQB1* alleles in the Caucasian population), resulting in only a few instances that did not correspond to canonical DQ types.

In the database of Genomic Variants and 1000-Genomes, low frequency copy number variations (CNVs) were observed in humans covering the RHOXF2 gene region (http://projects.tcag.ca and http://browser.1000genomes.org) [ 31, 32], supporting the proposed non-allelic recombinations mediated by the HERVs.

None of these changes were

Although, no clear bias was

This phenomenon is currently being observed in England and Wales post vaccine introduction http://www.hpa.org.uk and it is having major implications for the overall impact of the programme.

The grids were observed in a Jeol JEM 100CX II electron microscope (http://www.jeol.com) operated at 60 80 kV.

This phenomenon was observed in all the datasets we examined (see supplementary information at http://bioinfo.mbb.yale.edu/~kluger/artifact/GB_CHROMOSOME_DISTANCE.ppt).edu/~kluger/artifact/GB_CHROMOSOME_DISTANCE.ppt

DOI: http://dx.doi.org/10.7554/eLife.00184.007 Two bound metal ions were observed in each GsuK subunit.

No specific immunoreactivity was observed in control sections (see Figure S1 in Supplementary Material available online at http://dx.doi.org/10.1155/2013/760236).org/10.1155/2013/760236

In the ExAC database (http://exac.broadinstitute.org/), the P22S and E281K missense mutations have only been observed in a frequency of 0.0008% and 0.002%, respectively.