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Therefore, it is reasonable to hypothesize that significantly different values of PET image-derived heterogeneity quantification features may be observed in benign and malignant thyroid nodules, based on the different underlying physiopathological properties.
Even this, however, may not be definitive, because a slight capsular penetration can also be observed in benign tumours.
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T2-shine-through is observed in benign conditions such as cysts, post-operative seromas or tissue.
As high clusterin expression was observed in benign gonadotroph adenomas and in small slow-growing αGSU.PTTG pituitary tumors (Figures 3 and 4E), and also in LβT2 cells overexpressing mPttg (Figure 5A,B), we analyzed the effects of altering intracellular clusterin levels.
A similar phenomenon was observed in benign epithelial and stromal prostate cell lines.
tCho has also been observed in benign, normal, and lactating breast, therefore quantitation is vital.
With this antibody, no or only weak background staining was observed in benign cells.
Complete lack of M2-PK expression was observed in benign pancreatic ducts, premalignant lesions and cancer.
For ER-α, a similar expression was observed in benign diseases (Fig. 1a) and in CIS (Fig. 1a).
AR and DAX-1 immunoreactions were observed in benign diseases as well as in both cancer types (Fig. 1c,1d).
This reduction was observed in benign and malignant tumors and was not associated with increased expression of IGF1R.
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