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This hypothesis has been proved to be not reasonable.
Key propositions for the case (p = 0), which seem to be not reasonable from a practical viewpoint but actually serve as the basis for dealing with the case with sufficiently small (p > 0), are presented below.
The comparison of growth variables by randomized arm will be performed with either the two-tailed t-test or a non-parametric alternative (e.g. Mann Whitney test), should the normality assumption be not reasonable.
However, the case-only analysis relies on the strong assumption of the independence of gene and environment in the population, which might be not reasonable across all SNPs that are scanned in a GWAS.
As TGF- β can also contribute to epithelial mesenchymal transition (EMT) progression through transcriptional target genes, such as Snail, MMPs, and EMT-related genes, it seems to be not reasonable that cancer cells inactivate Smad4 to gain the resistance to TGF- β signaling.
Similar(55)
These sulky armies of middle-aged whites are not reasonable, and can't be reasoned with.
For this reason, unadjusted comparisons are not reasonable and should be abandoned.
"I did have a reason for being in a hurry, but my speeds were not reasonable.
It's not reasonable.
This is not reasonable.
"It is not reasonable," he said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com