For applications requiring a comprehensive transcriptome profile, coverage exceeding 10 million fragments per sample may be needed, with the understanding that increasing depth can lead to detection of sequences that may not represent bona fide transcripts.
Spain remains insistent, though, that another round of draconian steps would not be needed with the spending cuts and tax increases already in place.
Improved treatment options are needed with an increased emphasis on improving the therapeutic index.
Although economic realities may limit the ability to continually rescreen, strategies designed to capture those at highest risk are needed with the rapidly increasing incidence of type 1 diabetes worldwide and the highest observed annual rates in the youngest age-group (5.4% [4.8 6.1] for children age 0 4 years) (11).
According to the relationship shown in Fig. 6, more improvement to the current shelter planning is needed with the increase of evacuation population size, especially when the MIT exceeds their tolerance.
Such data are needed with the expected increase in the number of people who will develop HZ and HZ-related pain [ 11– 15].
A greater awareness of the importance of managing a patients' overall health status within the context of comorbidity is needed together with, increased research on comorbidity to provide an appropriate scientific basis on which to build evidence based care guidelines for these multimorbid patients.
New potato cultivars with increased yield and improved performance under biotic and abiotic stress will be needed to keep up with increasing global demand for food and the effects of climate change.
The local development plan for the area suggests a new bridge would be needed to deal with the increase in traffic flow caused by the site.
However, the greater increase in GP attendances for practices in the least-deprived quintile compared with the most-deprived quintile for the lung campaign warrants consideration, and further efforts are needed to increase engagement with, and impact in, lower socioeconomic groups.
