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Other additional biomarkers may be needed to subclassify phenotypes better [ 49, 50].
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We were unable to subclassify patients because our analysis only takes into account the most significant variant for each gene, and more significant markers may be needed to identify such subgroups.
Therefore, new factors, which can be used to subclassify grade 2 tumours, are needed for determining treatment strategy in this category.
Since the significance of basal cytokeratin or EGFR overexpression is not known and we lack validated assays, these features should not be used to subclassify TN tumours.
These features could affect the diagnosis and subclassification of NSCLC, so it may be difficult to subclassify the tumor by using routine hematoxylin and eosin (H & E) stained sections.
Theoretically, it may be possible to subclassify COPD populations, who phenotypically appear similar.
Only tumour size and radiation treatment were independent predictors of survival in this population and may be used to subclassify these patients.
Clinically, smoking history can be used to subclassify histologically similar tumors based on smoking status-associated molecular and clinical features, and can inform therapeutic decisions [ 3– 7].
In accordance with other international series, it was agreed that the Paris classification and the term 'laterally spreading type polyp' (LST) may be used to subclassify lesions further.
However, other approaches have been used to subclassify cases in psychiatry in relatively small samples.
Conclusion: It is possible to subclassify prolapse on the basis of morphologic changes in the levator ani by using MRI.
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CEO of Professional Science Editing for Scientists @ prosciediting.com