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(33) In our study, p-c-Met expression was frequently observed not only in tumor buds but also in larger tumor nests near the invasion front, suggesting that additional factor/s may be needed for cells undergoing tumor budding/sprouting.
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Indeed, hy3 mice have an increase in lipid in cells of the choroid plexus and ependyma [ 26], suggesting that Hydin function might be needed for cell homeostasis and/or signalling.
In humans, foveolar cells migrate to the surface rapidly (see online supplementary figure S1), but labelled parietal cells are seen in the isthmus at 67 days after IdU injection, 14 indicating that in the human being, a similar lengthy period is needed for cells to reach the gland base, confirming bidirectional flux.
Steve Crawley, the product marketing manager, says that a larger system using pumps for fuel delivery is needed for cells that can power notebook-sized products.
The analysis we have carried out indicates the aromatic triad in the active site of DinB is needed for cells to survive NFZ or MMS treatment because mutations in the aromatic triad impair in vivo TLS.
Cyclin B1 is needed for cells to enter mitosis, and therefore essential for growth of all cells, including tumor cells.
High cyclin D1 is needed for cells to pass the G1 checkpoint, and it was previously thought to be associated with increased proliferation and poor clinical outcome.
DOI: http://dx.doi.org/10.7554/eLife.02667.001 The kinase, Aurora A, is a human protein that is needed for cells to divide normally.
Functional liver tissue is needed for cell transplantations.
Indeed, we observed that that 4−7 RGD peptides per µm2 was needed for cell spreading and adhesion formation.
But he said that in practice, therapeutic cloning would "never, ever fly" because it is individualized cell therapy, not mass production, that is needed for cell therapies to succeed commercially.
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