Sentence examples for be necessary to reverse from inspiring English sources

Interestingly, IDH inhibition using the mutant IDH1 inhibitor AGI-5198 was not nearly as effective, which suggests that broader epigenetic therapies may be necessary to reverse more permanent changes induced by long exposure to mutant IDH.

She also said that another constitutional amendment may be necessary to reverse the problem.

To prove this, it would be necessary to reverse the sequence of study drugs, however, the fact that Dexamethasone has fewer severe side effects makes this unattractive.

One way to correct for such bias is to calculate the number of studies confirming the null-hypothesis that would be necessary to reverse a conclusion that a significant relationship exists [ 37].

If the severely agitated patient becomes hypoxic and hypercapnic as a direct result of the effects of agitation, therapeutic paralysis, intubation, and mechanical ventilation will be necessary to reverse deleterious end-organ effects [ 81].

Awareness of recent CDC surveillance case definition diagnostic guideline changes [ 9] and their limitations, awareness of alternative clinical presentations, an appreciation for the varied manifestations of EM, and the appropriate use of serologic testing will be necessary to reverse this trend.

Supporters said these measures were necessary to reverse years of economic stagnation.

New platforms and forms of communication are necessary to reverse a campaign of brainwashing that dates back three generations.

I don't know what is necessary to reverse this disgraceful decision, but if dynamite is required, then dynamite is indicated".

Mr. Porges, who called one of his reports about Genzyme, "Where's the Towel?" said new management was necessary to reverse course and break apart what had become a conglomerate.

To understand Lindauer's unlikely walk-on role in the history of the Iraq war, it is necessary to reverse your normal angle of vision and to imagine how she might have looked through the eyes of the diplomats and intelligence operatives who staffed the Iraqi Mission to the United Nations under Saddam Hussein.