It may therefore be necessary to develop selective FXR modulators.
Thus, it may be necessary to develop tailor-made guidelines at regional levels.
On some landscapes periodic fire may be necessary to develop and maintain oak-dominated savannas.
However, multiple NMR techniques may be necessary to develop a full profile of root-derived DOM.
It seems to be necessary, to develop other measurements for estimating eggshell quality without destroying the egg shell.
Where Federal statutes restrict the reimbursement of certain indirect costs, it may be necessary to develop a special rate for the affected Federal award.
To do so, it will be necessary to develop compatibility measures which should be assessed for each couple of immediate neighbour partners.
It may be necessary to develop interventions that attenuate these biological mechanisms in order to achieve long-term weight reduction in obese individuals.
To achieve meaningful reductions, it will be necessary to develop technologies that can be applied to both greenfield projects and to the existing fleet through cost effective retrofits.
In addition, it may be necessary to develop injury criteria and evaluate dummy biofidelity based on contact locations as this parameter depended on the impact mode.
For example, it may be necessary to develop standards that ensure non-bonus or fixed pay is put at risk, maximise claw back, or pay senior staff in performance-related bond".
