Sentence examples for be necessary for triggering from inspiring English sources

However, high densities of expression of functional α7-containing nAChRs in CA1 pyramidal neurons may not be necessary for triggering important cellular and network functions, especially if activation of α7-containing nAChRs occurs in the presence of positive allosteric modulators such as PNU-120596.

Wortmannin-treated cultures display a diminished capacity for radiation-induced up-regulation of p53 protein and expression of p21 WaF1, a p53-regulated gene involved in cell cycle arrest at the G1/S border; the treated cultures also exhibit decreased capacity for enhancement of CaMKII activity post-irradiation, known to be necessary for triggering the S phase checkpoint.

Enhanced expression of Oct-4, Sox2, and c-Myc in PDLCs and DPCs cultured in hypoxia was observed, suggesting that low O2 microenvironment may be necessary for triggering the expression of these stem cell markers to maintain the stem cell properties of adult PDLCs and DPCs, although the molecular signalling pathways connecting hypoxia and stemness are yet to be elucidated.

If so, both abundance of groundwater and abrupt increase in pore fluid pressure are necessary for triggering mud eruption.

Interestingly, only the tight attachment of hyphae to the root surface displayed the possibility of infection, suggesting that substantial interaction between the host and hyphae was necessary for triggering hyphae penetration.

We ask, for instance, why so many different receptor subtypes are necessary for triggering biological properties and functions, and if these receptors are more than the sum of their single entities.

Several in vitro observations have suggested that thermodynamic asymmetry governs the strand selection that is necessary for triggering efficient RNAi, in which only the guide strand of the siRNA duplex is incorporated in the RISC [21], [22], [23].

These results indicate that a retinylidene protein is necessary for triggering changes in cGMP levels during green light exposure.

The mechanism by which signaling is transmitted is unclear, specifically how substrate binding or conformational rearrangements during the transport cycle are necessary for triggering the receptor activity.

The mechanism of the receptor function is unclear, specifically whether substrate binding or conformational rearrangements during the transport cycle are necessary for triggering the receptor activity.

We further tested if acidity of the apple cider vinegar was necessary for triggering wild-type post-stimulation behavior by neutralizing apple cider vinegar to pH = 7.0.