Sentence examples for be necessary for replication from inspiring English sources

Furthermore, the helicase activity of Srs2 was shown to be necessary for replication to proceed past the hairpin [38].

He claimed that this pathogenic agent, which he named "prion," was unlike any other known pathogen, such as a virus or bacterium, because it consisted only of protein and lacked the genetic material contained within all life-forms that is necessary for replication.

The interaction between SL3.2 and 3′-X is necessary for replication (Friebe et al., 2005), while the interaction between SL3.2 and domain III of the 5′-UTR has been reported to inhibit IRES-mediated translation (Romero-Lopez and Berzal-Herranz, 2012, 2009), which is thought to play a crucial role in the switch between the translation and replication during the HCV life cycle.

We then focused our studies more closely on the DNA replication factor CDT1. CDT1 expression is necessary for replication fork progression during S phase.

Irinotecan inhibits the activity of DNA topoisomerase I, which is necessary for replication of DNA.

This mutation is located upstream of the rstA gene, which is necessary for replication of the CTX phage genome [ 20].

In Lp, the stringent response, and the RelA and SpoT proteins are necessary for replication inside host cells and initiation of the transmissive phase [ 67, 68].

The 3′ triplet, CCA, was shown to be necessary for efficient replication, but deletion of eleven nts to expose an internal CCA resulted in continued replication.

MCMV can express transgenes and can potentially carry rather large DNA fragments since its genome is large (about 230kb) and only about 80 genes appear to be necessary for its replication.

Further work will be necessary for external replication and validation of these results.

Although we predicted that the majority of the identified arthropod factors to be host species-specific, we hypothesized that few of the human homologues of the arthropod host factors may also be necessary for the intracellular replication of F. tularensis within human cells.