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It is logical to hypothesize that the negative regulator of PI3 kinase, PTEN, should also be necessary for regulating gastrulation cell movements in zebrafish, but no gastrulation defects was observed in zebrafish pten mutants [37].
The Sp1 site, with other promoter elements such as the AP-2 site, has been shown to be necessary for regulating constitutive expression of MMP2 [28].
In turn, these domains seem to be necessary for regulating protein turnover and help to establish functional differences between KLF6 and KLF6-SV1, whave have both been shown to play important roles in cancer initiation, progression and survival and for predicting outcome.
Because the circadian clock has a critical role in the flowering transition, the activities of antioxidative enzymes might be necessary for regulating flowering time and thermotolerance mechanisms [ 42].
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These knowledge systems were necessary for regulating livestock grazing patterns.
DND1 may be a cellular factor that is necessary for regulating some aspect of APOBEC3 activity, especially in germ cells.
The increased arrhythmicity in Kcnma1−/− recordings suggests that BK channels are necessary for regulating the day-night difference in SFR and shaping daily spontaneous activity rhythms in the SCN.
Mechanical stimulation is necessary for regulating correct formation of the skeleton.
Collectively, these findings demonstrate that PP2A also regulates FOXO3a activity in CD8+ memory lymphocytes and indicate that p47phox is necessary for regulating PP2A activity.
Thus, we conclude that the 9 nucleotides that Qrr1 lacks are necessary for regulating a subset of the Qrr targets including aphA, vibhar_00505, and vibhar_05691.
In turn, low mitochondrial ROS levels, which are produced during starvation for example, are necessary for regulating (through posttranslational oxidative modification) Atg4 activity when autophagy activation is part of a survival pathway [ 73].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com