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Findings by Lawley et al. [ 26] suggest apoptosis, however, may not be necessary for presentation of these autoantigens at the cell surface after exposure to UV light.
We chose the whole VP2 protein as well as the antigenic peptide so that we could rule out the possibility that sequences flanking the VP2121-130 peptide would be necessary for presentation on MHC class I molecules in the thymus.
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21 22 23 24 Although imaging in general showed a positive effect on patients' outcomes in acute appendicitis, the ideal diagnostic strategy for acute appendicitis remains a matter of debate, as imaging might not be necessary for certain presentations.
More than one case per topic can be necessary for common diseases which are often complicated/have co-morbidities at presentation.
The "balance" definition proposed in this paper includes a provision that the presentation of the "do nothing" option may be necessary for a balanced PtDA.
"Won't be necessary for either".
These will be necessary for heavier jobs.
Class II major histocompatibility complex (MHC) molecules are expressed by professional antigen presenting cells (APCs), and are necessary for the presentation of antigenic peptides to CD4 T cells and the subsequent initiation of an adaptive immune response.
We previously showed that the expression of the αvβ3 integrin is necessary for exogenous presentation of MMP-2 antigen.
One of the earliest hints that production of antigenic peptides was dependent on the proteasome was the observation that ubiquitination was necessary for the presentation of the model antigen ovalbumin [ 116].
During this whole process, under the selective pressure of antitumor CTL, the tumor can sometimes escape the immune response by losing the expression of genes that are necessary for the presentation of peptides to antitumor T cells.
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