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While multiple gene deletions or additions will likely be necessary for maximum robustness in the presence of furfural and 5-HMF from real-world substrates, this work further demonstrates that C. bescii is amenable to strain improvements through rational engineering.
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The tension they experienced precluded the relaxed, open concentration that is necessary for maximum academic performance.
Both ITS and ascorbic acid were necessary for maximum collagen incorporation into micromass cultures.
Whether a critical period of drought is necessary for maximum epizootic amplification also requires exploration.
Assuming that the parasites are exposed to the antimalarial drug at a sensitive stage, what duration of exposure in a single asexual life cycle is necessary for maximum effect?
While both DDR1 and DDR2 have been shown to recognize collagen I [ 1, 25] our results suggest that only DDR2 is necessary for maximum migration of NHLFs through collagen I matrices.
The optimization of styrene-degrading biofilters is necessary for maximum styrene elimination and cost-saving measures, thus warranting a comprehensive examination of the microbial communities within biofilters to enhance overall bioreactor performance.
The delay in tumour growth for VNP pRA-TR with 2 Gy radiation was significantly greater than the control treatments, VNP pRA-ZsG with 2 Gy irradiation and VNP pRA-TR alone, indicating that both TRAIL expression and induction by radiation were necessary for maximum growth delay.
Clinical evidence demonstrates coadministration of tumour necrosis factor inhibitor (TNFi) agents and methotrexate (MTX) is more efficacious than administration of TNFi agents alone in patients with rheumatoid arthritis, leading to the perception that coadministration of MTX with all biologic agents or oral disease-modifying antirheumatic drugs is necessary for maximum efficacy.
Previously, we determined that simultaneous treatment with IL-1β and LG268 leads to modest but significant inhibition of MMP-1 and MMP-13, and a 12- to 24-hour pretreatment is necessary for maximum inhibition of MMP levels in these cells by the RXR ligand, LG268 [ 21].
Chemotherapy was repeated every 3 weeks (unless a dose delay was necessary) for a maximum of four cycles.
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CEO of Professional Science Editing for Scientists @ prosciediting.com