Sentence examples for be necessary for differentiation from inspiring English sources

This epigenetic variation may be necessary for differentiation, but it also provides a mechanism for Darwinian evolution at the cellular level that may underlie age-related diseases such as cancer.

Thus, the withdrawal of IL-6 mediated STAT3 signaling may be necessary for differentiation to occur.

Since IL-6 was rapidly down-regulated prior to this time it is worth suggesting that IL-6 may be intimately involved in the proliferative process and the absence if IL-6 may be necessary for differentiation to occur.

From a tissue engineering[6] perspective, appropriate spatial, temporal and mechanical cues are likely to be necessary for differentiation of ESC-derived progenitors capable of generating functional substitutes for damaged or diseased tissue [2], [3], [7], [8].

Follow-up imaging or an angiography may be necessary for differentiation.

17 Further diagnostic studies would be necessary for differentiation of such subgroups, in particular with respect to the necessity for therapy with inhaled corticosteroids.

Gabaldón et al. ([2005]) demonstrated that Nitric oxide (NO) production was necessary for differentiation of TEs derived from Z. elegans mesophyll cells.

In embryonic stem cells, PcG proteins regulate stem cell pluripotency by maintaining repression of alternative lineage genes that are necessary for differentiation of stem or progenitor cells into various tissue types [35].

Taken together, the results demonstrate that Sox2 is necessary for differentiation and maintenance of Clara, ciliated, and goblet cells from Clara cell progenitors, and may play a role in directly regulating the expression of differentiation dependent genes in each of these cell types.

In neuronal stem cells, loss of REST function is necessary for differentiation into neurons [ 19].

Myoblasts induce the expression of MyoD1 which is necessary for differentiation into fusion-competent cells.