Sentence examples for be necessary for binding from inspiring English sources

The octanoyl group has been proposed to be necessary for binding to the GHS receptor rather than for binding to membranes.

By contrast, the entire mature sequence (∼21 nt) seems to be necessary for binding target sites in plants (Axtell and Bowman 2008), and therefore it would be difficult to generate miRNA genes from hairpin structures in a genome.

This domain was shown to be necessary for binding to Rab5a and for GDP/GTP exchange activity, and indeed RIN1 was characterized as the Ras effector protein that connects Ras signaling to the control of endocytotic processes [3].

In order to shorten the half-life, we replaced the CH2 domain, which has been previously shown to be necessary for binding to FcRn (Mueller et al, 1990), with a hinge domain (H'; Glaser et al, 2005) and a poly-glycine-serine linker (Glaser et al, 2005; Fig  1A and Supplementary Fig S1A), and named this molecule Short-trap.

The putative path for RNA agrees well with biochemical data indicating that a 3′ single strand overhang of 7 10 nt is necessary for binding and hydrolysis by RNase II.

In contrast, LigB repeat 9 was necessary for binding fibronectin and its N-terminal fragment.

The 5' stem-loop structure (stem 1) is necessary for binding HEXIM1, which is a prerequisite for binding P-TEFb; in the next step, the 3'-terminal hairpin of 7SK (stem 4; [57]) interacts with P-TEFb [37].

Indeed osteoclastogenic SCs express intercellular adhesion molecule-1 (ICAM-1) which is necessary for binding to OC precursors [39], while matrix-producing osteoblastic cells are ICAM-1 negative [40].

The Roc NH2-terminus is necessary for binding to Cullin protein [26] and forms a β-strand that makes an inter-molecular β-sheet with the Cullin protein [11], [14].

We mapped the interacting domains between VAB-19 and EPS-8 in yeast (Figure 1A) and found that the central domain of EPS-8 (residues 272 502) was necessary for binding VAB-19.

Among the newly detected Jun-associated protein candidates, Cebpg, Creb3, and Tef are intriguing proteins as Jun-associated transcriptional regulators, because they contain basic regions near the leucine heptad motifs, which are necessary for binding with regulatory sequences on the genomic DNA; many known Jun-associated proteins contain such structures.