Sentence examples for be necessary based on from inspiring English sources

In vivo BE studies for higher strengths may not be necessary based on (1) clinical safety and/or efficacy data on the proposed dose and the need for the higher strength, (2) linearity of pharmacokinetics over the therapeutic dose range, and (3) the same dissolution procedures being used for all strengths and similar dissolution results obtained.

These protocols should serve as guidelines only, and modifications may be necessary based on graft selection, presence of articular cartilage involvement, and surgeon preference.

The latter would be necessary based on the utilisation of a modelling approach to identify the optimal irrigation strategy associating a water amount with a crop yield (Yc).

Serum troponin-T, serum creatine kinase-MB and chest x-ray may be necessary based on clinical and ECG findings.

Modifications will definitely be necessary based on faculty experience and expertise in ultrasound, available technical resources and support [ 3].

More aggressive overall glycemic control for CFRD may be necessary based on recent reports that HbA1c underestimates a true glycemic index in CF patients [ 14].

Mr. Madrid also argued that the demolition is necessary, based on the building's deteriorating condition.

"Do I personally believe it's necessary, based on the man I know?" Mr. Quijano said.

After its 2009 drug oversight meeting, the F.D.A. decided that no action was necessary "based on available information".

An adjustment is necessary based on the geomechanical and geometric parameters of the backfill.

This suggests the most recent graduates were less likely to correctly identify uveitis cases where IMT induction is necessary based on the management guidelines [5].