Sentence examples for be mutated in certain from inspiring English sources

Another advantage is that these oligonucleotides are not dependent on the half-life of the splicing factor (and thus can act immediately as seen in Fig. 2a) or on any cellular mechanism that can be mutated in certain cancer cells (e.g., siRNAs, which depend on the cellular machinery).

PTEN directly regulates the activity of PTEN-induced putative kinase 1 PINK), a protein kinase that localizes to mitochondria where it inhibits cytochrome c release, and known to be mutated in certain forms of familial Parkinson's disease [42].

The PDGF receptor genes have also been found to be mutated in certain malignancies.

Blind cavefish that have adapted to annual cycles of starvation and binge-eating have mutations in the gene MC4R, the same gene that is mutated in certain obese people with insatiable appetites, according to a new study led by Harvard Medical School geneticists.

Bub1 (budding uninhibited by benomyl) is a serine/threonine kinase that has a function in the mitotic spindle checkpoint and is mutated in certain types of human cancer [ 49].

If h i or h j is a gene that is observed to be mutated in a certain type of cancer, (h i, h j ) is then a predicted SL pair in the human cancer.

However, certain chromatin remodeling genes (MLL1, MLL2, MLL3, BAP1, PBRM1, EED, and ATRX) were found to be mutated in 7/22 (32%) of intraductal tubulopapillary neoplasms and 27% harbored phosphatidylinositol 3-kinase (PI3K) pathway (PIK3CA, PIK3CB, INPP4A, and PTEN) mutations.

Twenty-nine genes were found to be mutated in more than 10% of patients (Fig. 1), including many commonly mutated genes in SCLC12.

In our study, we discovered a variety of genes previously unknown to be mutated in TCC.

Interestingly, the Pol ß gene appears to be mutated in a large percentage of tumors.

SAMD9 was recently found to be mutated in normophosphatemic familial tumoral calcinosis.