Sentence examples for be mutated at a from inspiring English sources

iii) Mutation: The new created individual will be mutated at a definite point in the chromosome.  .

Among the genes harboring significant somatic variants, we found CDKN2A to be mutated only in the never-smokers and past smokers, PIK3CA to be mutated only in the smokers, and TP53 to be mutated at a 20% greater frequency in the smokers, CASP8 mutation has a 12% greater frequency in those that consumed alcohol or chewed tobacco.

TSC1, as well as TSC2, that constitute the mTOR regulatory tuberous sclerosis complex were found to be mutated at a combined frequency of 15%.

For instance, compared to the noted low frequency of mutation for numerous genes across all breast cancers, TP53 (37%), PIK3CA (36%), and GATA3 (11%) were the only genes found to be mutated at a level greater than 10% overall.

Another member of this gene family, KMT2C (alias, MLL3), is also found to be mutated at a lower frequency in FL and DLBCL, providing some suggestion of functional redundancy in lymphomagenesis.

These elements are peppered throughout the human genome and contain a unique sequence that can be mutated at a single base to create a new splice site and give a different version of a protein [ 47].

In microsatellite unstable tumours MBD4 can itself be mutated at an exonic polynucleotide tract.

Recently, the chromatin regulator genes CHD7 and CHD8 were found to be mutated at an enriched frequency in CIMP-positive colorectal cancers compared to CIMP-negative.

The promoter was mutated at a single TCF4/Lef1 binding site or both binding sites at a time.

In order to map the RNF10-binding motif within the SSE sequence, we analyzed a series of oligonucleotides in which 2 bases were mutated at a time.

10.7554/eLife.00825.012 Figure 4. MYBL2 is mutated at a low frequency in MDS.