Sentence examples for be much less potent from inspiring English sources

Importantly, mini-yCD3 was shown to be much less potent in the induction of T-cell proliferation, cytokine release (interferon-γ and interleukin-2) and early activation marker expression on the cell surface (CD69 and CD25) than parental yCD3.

Such interaction might be highly relevant since in vivo administered recombinant BMPs (rBMPs) seem to be much less potent than in vitro.

Some of those metabolites have been synthesised and shown to be much less potent than the parent compound at inhibiting CDK2 (Nutley et al, 2005).

None of the patients in our study received this agent; rather the most frequently used systemic agent was BCNU, which appears to be much less potent.

SU6656, and Src-1, two other small molecule SFK inhibitors [ 25, 26] were also tested, but found to be much less potent than PP2 in reducing overall pY levels in SW620 cells and did not effectively inhibit Odin tyrosine phosphorylation (not shown).

And the ethnic factor was much less potent than in many elections elsewhere.

But the hitters who will bat behind him are much less potent -- as Manager Bob Brenly has ascertained.

The compounds were much less potent on mammalian protein prenyltransferases.

It is interesting to note that the 4′-O-methylated analog 15 (IC50 > 40 μM) is much less potent than 16, indicating that this 4′-O-hydroxy group is perhaps important for the anticancer activity of glycosylated podophyllotoxin derivatives.

In the presence of purified anticoagulant heparin and derivative, FGF7 has the similar activity as protamine sulfate for reversal of anticoagulant effect, while FGF1 is much less potent than FGF7.

An anti-ADM antibody directed against the N-terminus substantially increased the survival of mice in a CLP model (HR = 0.077 (CI = 0.0189 to 0.315), p = 0.0004), whereas other antibodies with similar affinities but different epitope specificities were much less potent.