Patient compliance may be most difficult to achieve in chronic but generally asymptomatic illnesses such as hypertension.
But, the pope added, "Italy's social and cultural identity, and the civilizing mission it has exercised and continues to exercise in Europe and the world, would be most difficult to understand without reference to Christianity, its life blood".
To listen to Mrs. Clinton, and to judge from her past record, it would be most difficult to give credence to the accusations maligning her as an anti-Semite.
"And isn't it tragic that instead of those moneys going to improve facilities, or hire more Park Rangers, that taxpayers will be paying for studies that quite frankly will be most difficult to carry out but will prove that the latest P.W.C.'s are superior to other vessels".
One point on which everyone agrees, however, is that, of all the potentially dangerous radioactive isotopes, it will always be most difficult to detect highly enriched uranium-235, one of the two materials, along with plutonium, used to make fission weapons.
On the contrary, gene expression in epidermal tissues seems to be most difficult to silence.
