Hence, ethanolic extract is more toxic compared to aqueous extract, as the IC50 of ethanolic extract was 2.6-fold higher than that of aqueous extract.
Although TBI-containing conditioning seems to be more toxic as compared to its busulfan-containing counterpart, the speed of engraftment, event-free survival and relapse rate are not significantly different (Clift et al, 1994).
Due to their direct mutagenic potency, OPAHs may be more toxic to humans compared to their parent PAHs [ 11, 12].
This choice is in contrast with data from randomized trials conducted in elderly women in whom CMF-like was demonstrated to be more toxic and less feasible compared to anthracyclines, like AC regimen [ 20].
Most interestingly, the compound was found to be more toxic towards glioma cells as compared to other cell lines of different origin including MCF-7 (breast cancer), U2OS (osteosarcoma) and PC-3 (prostate cancer) [ 32].
In addition, the effect of fatty acids has been shown to be more toxic in the brain and lung compared to the effect of triolein [ 5- 9, 17, 29].
The high MW oligomers appear to be more toxic in vitro and in vivo compared to Aβ42 monomers, low MW oligomers, and fibrils, although Aβ dimers isolated from the AD brains were shown to impair synaptic plasticity.
The dust in the metro system was shown to be more toxic than ambient airborne particulates, and its toxicity was compared with welding dust.
Whereas the concentration of PM10 2.5 was higher in the west compared with the east, the chemical constituents present in PM10 2.5 may be more toxic in the east.
