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If the subject under review was more widely researched, synthesising and translating the synthesis may be more problematic due to the quantity of data and potential contradictions in the findings.
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The assignment of Lbx2-type genes was more problematic, due to incomplete sequence information for chicken and frog.
In psychiatry, biomarker research is more problematic due to the difficulty in illuminating the pathophysiology of psychiatric disorders.
Compared to adults, DXA assessment of body composition in children is more problematic due to their smaller size and tendency to move.
Linking sensitization and culture to the panel of fungi cultured in this study is more problematic due to the lack of reagents for the majority of species identified.
Regions of low microtubule density led to well resolved STORM images (e3), whereas the imaging of crossing structures, or regions of high labeling densities, was more problematic due to rarely isolated single emitter patterns (e2).
The impact of a natural gas cut-off would be more problematic, not so much due to prices, but the intertwined dependence of many European states on pipelines and flow emanating from Russia.
Besides homopolymers, repetitive DNA is known to be more problematic for 454 sequencing than for Sanger due to the shorter length of the 454 reads.
Misclassification due to self-reported ethnicity may be more problematic when examining the genetic associations with disease (Burchard et al. 2003).
The injury to Peterson could be more problematic.
Nonresponse bias might be more problematic.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com