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Tests showed it to be more potent at reversing the effects of opioids than any antagonist synthesized so far.
In general, compounds 2c and 3c were found to be equipotent at all the three different doses selected and with respect to BL 11282, both the test compounds were found to be more potent, at all the time points.
Within the time constraints of an outbreak occurring within a small susceptible pool, treatment may be more potent at inducing resistance than prophylaxis [4] [10], depending on the relative fitness and seeding rate assigned to emergent drug-resistant viruses [6].
The 're-educated' macrophages appeared to be more potent at inhibiting T cell proliferation.
Docetaxel, which is the study medication of this trial, appears to be more potent at inhibiting angiogenesis in vitro and in vivo than paclitaxel [ 28], which is the standard medication for treatment of advanced ovarian cancer patients.
Although this compound does appear to be more potent at inhibiting MEK and ERK activation in an SK-Mel-2 cells (NRASQ61R) compared with vemurafenib, it still induces paradoxical activation, and similar to other Type 2 inhibitors (sorafenib, RAF265) inhibits multiple kinases in addition to RAF.
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But the Mustang convertible's V-6 is more potent, at 306 horsepower, and the Ford weighs 400 pounds less.
The lab has shown through sophisticated molecular-binding experiments that Chlor-Trimeton is more potent at grabbing and hanging onto the histamine receptor than any other antihistamine it has tested.
However, both PRP and PRF preparations were more potent at stimulating fibroblast proliferation and collagen deposition than PPP preparations.
Although both bio-AgNPs and chem-AgNPs could cause MTP collapse, bio-AgNPs were more potent at producing depolarization than chem-AgNPs.
Li Ying's group in Shanghai synthesized artemisinin derivatives that were more potent at killing malaria parasites and had more desirable chemical properties (such as solubility in water), making them better drug candidates than natural artemisinin.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com