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Here, we present data to show that targeted inhibition of VEGF-Axxx isoforms with Exon8apab, a polyclonal antibody specific to the exon8a (CDKPRR) amino acid sequence, is as effective as current anti- panVEGF-A therapeutics but may be more physiologically applicable in the treatment of VEGF-mediated pathologies.
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The binding affinities here would be more physiologically relevant and provide more precise understanding in ESCRT pathway of lysosomal degradation.
However, there are many potential combinations, and using a natural matrix would be more physiologically relevant.
By mimicking these crucial in vivo characteristics through use of 3D cultures, co-culture systems and acidic culture conditions, an in vitro cancer model/microenvironment that is more physiologically relevant may be engineered to produce results more readily applicable to the clinic.
This work led to the development of a cell-based model of coagulation that is more physiologically relevant than the earlier "cascade" model.
It's time that both public awareness and retail options drive a choice for lighting that is more physiologically compatible to what nature designed.
Firstly, neurotrophin delivery is more physiologically relevant in terms of amount and dose rate.
In comparison, term infants with appropriately developed airways are more physiologically robust.
Thus, the results are likely to be more clinically applicable.
For these individuals, the actigraphy method may be more applicable.
I have a feeling it would be more pertinent than a physiologically perverse rabbit laying eggs in your kid's mouth.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com