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Whether clonally-derived MSC versus specific MSC populations will be more efficacious for particular applications, remains to be determined.
This suggests the RYGB surgery may be more efficacious for resolving diabetes if performed soon after diagnosis in subjects with low HbA1C levels.
Polyfunctional cells are thought to be more efficacious for two reasons: first, they bring to bear, on each target cell, a wider range of effector functions simultaneously (as opposed to requiring the simultaneous recruitment of multiple effector cells).
As previously demonstrated, targeting multiple pathways is likely to be more efficacious for eradicating tumor cells than targeting EGFR alone (Müller et al., 2014).
In comparison with dronedarone, amiodarone may be more efficacious for maintenance of sinus rhythm, but it has a poorer side-effect profile, particularly with long-term use.
For example, TVR and boceprevir were compared in a MTC meta-analysis [ 23], and the indirect evidence suggests that TVR may be more efficacious for prior relapse but not for treatment naïve patients.
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This weakening of explosions was more efficacious for higher concentrations of methane than it was for lower concentrations of methane.
The results indicated that oxcarbazepine was more efficacious for relief of peripheral neuropathic pain in patients with the irritable vs the non-irritable nociceptor phenotype [23].
Therefore, the vAgEGTΔ-lacZ was more efficacious for the control of A. gemmatalis larvae (in bioassays) compared to wild-type AgMNPV.
As compared with clonidine, nefopam was more efficacious for the prevention of postanaesthetic shivering during the perioperative period.
Another comparison of two agents examined OROS methylphenidate and atomoxetine over several weeks, with the conclusion that OROS methylphenidate is more efficacious for core ADHD symptoms [ 48].
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