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Certain modalities of treatment have been shown to be more efficacious at one or more of these time periods.
2. Group education (in the form of the Osteoporosis Prevention and Self Management course) will be more efficacious at changing these lifestyle behaviours than an information leaflet alone.
This may relate to the short duration of tamoxifen treatment, because 2 or 5 years is now believed to be more efficacious, at least in other settings.
This may also explain why treatment with L-GSH seems to be more efficacious at much lower concentrations than NAC, as cells treated with NAC will have to produce new molecules of rGSH utilizing their own enzymatic machinery.
Metoclopramide may well be more efficacious at a dose of 20 mg, but currently there is no evidence to support this in the absence of an adequately powered and randomized study.
The effect of FA and ASP was initially evaluated by calculating the IC50 values and then by combining the ineffective concentrations to exhibit an additive or synergistic effect against the pancreatic cancer cells proving to be more efficacious at lower concentrations.
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Additionally, they may be more efficacious as a combinatorial treatment.
Cytisine and varenicline have a similar efficacy at α4β2*, α3β4*, and α7 rodent nAChRs, but cytisine is more efficacious at α6β2* nAChRs (Grady et al, 2010; Salminen et al, 2004).
In tests with various human cancer xenograft models, capecitabine was more efficacious at wider dose ranges than either 5-FU or 5′-DFUR and was significantly less toxic to the intestinal tract than the others in monkeys.
40 Moreover, O'Brien et al showed that rituximab was more efficacious at higher doses in CLL patients.
Colloidal agents are more efficacious at restoring plasma volume compared with crystalloids, per unit of fluid given [ 1, 17].
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CEO of Professional Science Editing for Scientists @ prosciediting.com