Things could not have been more different across the street a couple of hours later.
An additional advantage is that the data can be collected in a controlled manner, and once collected it is likely to be more comparable across different settings (Badland et al. [2010]).
As can be seen, sentiment-expressing words like "great" are not so frequent within a particular review, but can be more frequent across different reviews, and a good feature selection method for SA should take this observation into account.
In conclusion, although some scientists believe that results from testing gene sets rather than from individual markers would be more stable across different samples in the population and, thus, easier to replicate [56,57], enhancing robustness of pathway-based approaches or repeatability of the significance testing results in analysis of pathways still remains to be a difficult task.
Further, strong relationships could be expected to be more consistent across the different measures.
To be more consistent across our different analyses, we have now specified a criterion for this limitation: we have constrained the number of clusters so that no more than 5% of all the genes in the analysis belong to "non-representative" small clusters, defined as containing less than 1% of all the genes in the analysis.
The benefit of an analysis at the functional rather than gene level is that the results of such analysis can be more consistent across studies because different tumors may suppress or activate the same function through different genes, making prostate tumors heterogeneous at the gene expression level and much more homogeneous at the pathway level.
A benefit of using this checklist is that the evaluation of the studies can be more easily compared across different types of studies, and this evaluation process can be made visible for readers and evaluators.
