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Since daily activities in the elderly often require sustained intense muscle contractions (e.g. when bearing shopping bags), these may be more challenging given the reduced muscle strength, and could explain the common sensation of fatigue.
Importantly, they need to be assessed in terms of their impact on QoL measures and survival, although the latter is likely to be more challenging given the availability of multiple survival-prolonging treatments.
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Applying the model of CA to predict the estrogenic potency of a real-world chemical mixture such as WwTW effluent is more challenging, given the complex chemical matrices involved.
While in-class troubleshooting is more challenging given the diversity in computer operating systems brought to the classroom, students are often able to directly apply their knowledge to their own data set located on the same computer, and students leave the workshop with a working and familiar tool environment.
Unlike acute or surgical pain, where the nature and timing of the pain stimulus can be controlled, imaging FM pain is more challenging given that neither the experimenter nor the patient has the ability to systematically manipulate the characteristics of the condition [ 18].
That may not seem a particularly high mountain to climb, but it may well turn out to be more challenging than Everest, given that litigation and complaints against the banks show no sign of diminishing.
Economic recovery may be more challenging in community B, given the dramatic impact to businesses.
That said, this sort of change makes more sense on the Apple TV App Store, given its user interface which is operated by remote and can be more challenging to navigate.
Some locations, of course, will be more challenging than others.
Whereas determining the mechanism regulating the expression of the secretome is important, the task is made more challenging given that some of the proteins are released during cell death [ 127].
Determination of the higher-level role of the protein in modulating individual and colony-level behaviors will be even more challenging, given our profound ignorance of fire ant pheromonal systems and the behaviors involved in regulation of colony queen number.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com