Sentence examples for be modulated upon from inspiring English sources

In a second group, embracing members of the three studied enzymes, the ability to be modulated upon effector binding depends on the ratio between the kcat of the engineered enzyme and the kcat of the intact enzyme.

Our new data indicate that, in inflammatory settings, expression of JAM-3 may be modulated upon AnxA1 administration (pharmacological studies) or AnxA1 deficiency (patho-physiological investigations).

For example, proinflammatory pathways are known to be involved in the pathophysiology of PPCM [ 8, 23], which appear to be modulated upon treatment with bromocriptine [ 9, 23].

DRUGSURV provides multiple query options to explore systematically the effect of genes, which are known to be modulated upon drug treatment on survival in different cancers and clinical conditions.

The function of inflammatory cells is associated (in part) with the activation status of the cells' receptors, which can be modulated upon priming with inflammatory mediators, such as cytokines, chemokines and bacterial products.

Studies that were carried out on other viruses like herpes simplex virus (HSV) and human immunodeficiency virus (HIV) indicated that the expression of GABA A receptor on the target cells could be modulated upon the viral infection [ 18, 19].

We recently showed that the miRNA expression profile of HBMVECs was modulated upon exposure of these brain endothelial cells to glioblastoma cells [11].

From our data, a number of genes whose expression is modulated upon the loss of PKBα are known to be involved in pre-TCR and/or TCR signaling and T cell activation.

Indeed, very few genes of this family are modulated upon EGF stimulation, mostly in a down-regulation manner (Fig. 8D; see Table S2 for complete C3H10T1/2 array results, n/a for skin and somites explants).

Overall, these results provide evidence that both the host and viral miRNA regulation layers are modulated upon PRV infection of the PRV-DCs experimental system, and strongly suggest that their interplay is part of the process to establish latency.

We assessed whether expression of DNA methyl transferases (DNMT) was modulated upon Len/VD3 treatment.