Indeed, the possibility that IL33 signaling functions are modulated through its interaction with CCN3 is in line with previous observations that associated CCN proteins to inflammation.
For example, GacA is a pleiotropic regulator in Pseudomonadales, whose activity is modulated through its phosphorylation by the histidine kinase GacS [ 5].
In this context, it has been reported that the effects of Egr-1 on transcription are modulated through its phosphorylation by casein kinase II [ 41] and extracellular signal-regulated kinase (Erk) [ 42].
Here, we hypothesized that the incorporation, density, and stability of surface-presented avidin could be modulated through varying the lipophilicity of its fatty acid conjugate partner.
Here, we hypothesize that involvement of the IL-10 molecule in HIV-1 infection and pathogenesis could be modulated through complex interactions among IL10 and its related genes, especially those (IL19, IL20 and IL24) in the flanking genomic region and the IL-10 receptor genes (IL10RA and IL10RB).
Rather, the function of TTP seems to be modulated through interactions with specific proteins that alter its subcellular localization.
METH-1 protein function may be modulated through proteolytic cleavage at multiple sites.
Therefore, glucose-sensitivity of these PBA-based organogels could be modulated through alkyl chain length.
This suggests that the activity of curcumin toward maspin expression may be modulated through the p53 pathway.
Therefore, by modulating the expression of specific genes, the differentiation of stem cell can also be modulated through manipulating the key transcription factors [16, 17].
