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Recently, it was shown that several human multidrug resistance (MDR) ATP-binding cassette (ABC) proteins could be modulated by specific TKIs.
Discrimination of large numerosities thus emerges later in development and appears to be modulated by specific experience with social groups.
In addition, ethanol effects on the lipid dynamics could be modulated by specific ligands at MOP, as discussed in the following section.
DNA methylation is a reversible phenomenon which can be modulated by specific agents.
These findings indicate that the propensity to form filaments can be modulated by specific mutations in Gln1.
Earlier studies have shown that glioma cells express PPAR γ and that the levels of expression can be modulated by specific agonists (Morosetti et al, 2004).
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Allosteric enzymes exhibit a catalytic activity that is modulated by specific effectors, through binding to receptor sites that are distinct from the active site.
In this review, we discuss recent literature demonstrating that distinct molecular pathways are modulated by specific environmental inputs, the output of which regulates leaf dissection.
Structure function studies have revealed that fast macroscopic inactivation of CaV3.1 is modulated by specific residues in the proximal C-terminus and in the transmembrane domain IIIS6.
This article surveys our understanding of transporters that are modulated by specific pathogens and the mechanism(s) involved, thereby illuminating targets that might be exploited for new therapeutic approaches.
In two different species, we also present evidence that the barrier separating conscious and unconscious states is amenable to genetic and pharmacologic manipulation and is modulated by specific arousal-promoting mechanisms.
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