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Our data also suggest that the initial step of DNA replication may be modulated by oxidative stress.
This result indicated that the number of ISCs or enteroblasts could be modulated by oxidative stress.
Although CYP1A2 activity was not associated with breast density levels in premenopausal women, there was some evidence that the relationship may be modulated by oxidative burden.
Because the OGG1 promoter region contains the Nrf2 binding site, OGG1 gene expression may be modulated by oxidative stress resulting from exposure to As in this population.
In yeast, the MAPK Hog1 pathway, which can be modulated by oxidative stress, is known to regulate CK2- and Atg32-dependent processes in mitophagy.
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We firstly examined whether the expression of aging-related SIRT3 is modulated by oxidative stress in granulosa cells.
Recent evidence showing that CFTR expression and function are modulated by oxidative stress [32] [33] [34] and that CFTR controls extracellular glutathione levels [8] [9] [10] suggest that loss of CFTR function may result in a poor adaptive response to oxidants.
This could be modulated by acute changes in systematic oxidative status [ 22].
Similarly, Mazen et al. reported that myocardial STAT3 signaling might also be modulated by cardiac redox status and attenuated by oxidative stress during heart failure and other acute or chronic cardiac diseases 56,57.
It has been proposed that both the rates of telomere shortening and replicative senescence can be modulated by simply modifying the amount of oxidative stress, which leads to DNA breaks accumulating at telomeres.
Another possible source of these adducts is related to oxidative processes (Arif et al. 2006), which may be modulated by dietary antioxidants.
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