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Cancer cell morphology can be modulated by microRNA (miRNA or miR) activity [5], [6], [7].
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However, it involves a tag SNP that is in linkage disequilibrium with other SNPs in the 3'UTR region that could be modulated by microRNAs.
The inhibition of specific mRNA translation is modulated by microRNA depletion through lncRNAs harboring microRNA binding sites.
This in turn provides a broad range of transcripts and pathways that could potentially be modulated by small RNAs, perhaps including siRNAs that function as microRNAs.
be modulated by PTR.
Adult neurogenesis is a highly plastic process, which can be enhanced by environmental stimulation and physical exercise (Kempermann et al., 1997; van Praag et al., 1999) and it is modulated by epigenetic mechanisms, microRNAs (Cheng et al., 2009; Yoo et al., 2009; Ma et al., 2010), and growth factors.
Pathological cardiac hypertrophy and fibrosis are modulated by a set of microRNAs, most of which have been detected in biologically complex animal models of hypertrophy by arrays with moderate sensitivity and disregard of passenger strand (previously "star") microRNAs.
The expression of genes important for development of atherosclerosis is modulated by a variety of elements, including microRNAs (miRNAs).
A passenger is a protein-coding gene or microRNA whose expression is modulated by the driver molecular aberration.
Fibrotic responses are modulated by transcriptional activators and cofactors, epigenetic factors, and microRNAs that can amplify or inhibit ligand-induced signaling.
Epigenetic regulation of gene expression is modulated by changes in DNA methylation, covalent histone modifications, and microRNA [ 15- 17].
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