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It may be the case that any 'heterozygote advantage' in 5HTTLPR may be modulated by developmental stage.
Human neurospheres are likely to imitate basic processes of brain development, and these processes can be modulated by developmental neurotoxicants.
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In order to understand if the expression of atTOC159 homologous genes was modulated by developmental signals in reproductive tissues, GUS activity of flower buds and different stages of siliques collected from various transgenic plants was determined.
However, our knowledge is limited as to how the transcriptomes, proteomes and metabolomes involved in wood development are modulated by developmental and environmental signals to cause within-tree variation in wood properties.
Its expression is modulated by developmental, hormonal, dietary, and pharmacological factors, and it may change in response to specific diseases such as cholestasis [ 53] or alcohol-induced liver injury [ 54].
The marked protection against breast cancer afforded women by an early first full-term pregnancy has important clinical implications for designing chemopreventive approaches to breast cancer and, more generally, for understanding how cancer susceptibility can be modulated by normal developmental events.
The methylome is not immutable, however, and can be modulated by the environment, different developmental stages [ 18], or prolonged tissue culture [ 19].
One explanation is that, as these responses may be integrated over long periods of time, there is greater opportunity for them to be modulated by broad climatic and developmental factors.
Fine-scale regulation of developmental processes could be modulated by differential regulation of one or more components, allowing for a great degree of plasticity.
Results indicated that human germ cell formation and developmental progression could be modulated by the DAZ gene family with human DAZL shown to function in PGC formation, whereas the Y chromosome homolog, DAZ, and closely related autosomal homology, BOULE, promoted later stages of meiosis and development of haploid gametes.
Our work suggests that auxin signals through this cell division/cell expansion phase may be modulated by an ARF gene (ARF106) that is up-regulated during these developmental time points and co-locates with a stable QTL for fruit weight.
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