In order to improve the implant performance and to reduce implant related infections, titanium (Ti) surface was modified to simultaneously improve cell-material interactions and antimicrobial activity.
However, the ultrasonication step was modified to simultaneously perform a basic hydrolysis using different concentrations of NaOH.
Consideration was given to how these designs might be modified to produce the appropriate force system to allow both movements to occur simultaneously.
A PCR amplification reaction targeting the deletion breakpoint in normal, heterozygous and homozygous mutant individuals with the Filipino deletion was modified to detect simultaneously the normal and mutant alleles using three PCR primers 45F: 5' TCA GAA GCA GAG CTA CTC AG 3'; 45R1- 5' GTC TAT GCA GGT GTG TAG ACA 3' and 45R2: 5' CAT TTA GCT CCC ACA CTC CT 3'.
These include dual-CAR targeting strategies (Lanitis et al., 2013; Pegram et al., 2014), in which T cells are modified to express simultaneously two CARs with different antigen specificities to ensure that T-cell activation only occurs on tumour cells, where both antigens are present (Kloss et al., 2013).
For this purpose, the parameter estimation procedure has been modified to estimate the parameters simultaneously for different systems involving common pairs.
For example, nanocubes and nanorings were modified to package multiple siRNAs that simultaneously target different regions of the HIV-1 genome, thus limiting viral escape due to mutations.
The scheme is modified to efficiently account for multiple functionals simultaneously.
The original algorithm was modified to align the timing references of base stations to simultaneously transmit on downlink frames, and of user terminals to simultaneously transmit on uplink frames.
In summary, the regulatory pathway was modified to reconstruct the regulatory network of expression of cellulolytic enzyme genes, by simultaneously strengthening induction and relieving repression.
