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Daily doses may be modified for toxicity to 37.5 mg and 25 mg, in line with standard clinical practice.
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Five TTs (15 %) were modified for toxicity (dose reduction or temporary interruption).
PEI can, however, be modified for reduced toxicity, and its free amine groups can be used to conjugate cell binding or targeting ligands [17 19].
This will later be modified for Height.
These steps should be modified for drivers.
The treatment doses were modified for the following reasons: haematologic toxicity (66.6%), neuropathy (16.6%), fatigue (8.3%), and vomiting (8.3%).
The dose was modified for each patient based on haematologic or non-haematologic toxicity.
This interview has been modified for clarity.
The gefitinib dosing schedule could be modified to every second day for patients with severe toxicity: pulmonary toxicity (except for cough, forced expiratory volume in 1 second, hiccoughs, interstitial pneumonitis/pulmonary infiltrates) ≥ grade 2, or grade 3/4 diarrhea, mucositis, liver dysfunction, hematologic toxicity, skin toxicity, or ocular toxicity.
For example, susceptibility to lead toxicity can be modified by several dietary factors.
For studies on structure activity relationships, results demonstrate that the side alkylamine group can be modified with preserved activity, but that this modification is associated with increased toxicity.
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