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These data further imply that the core transcriptional machinery may be modified by specific signalling pathways in order to alter the transcriptional regulation of gene sub-sets.
Dual-task postural control can be modified by specific training.
To date, a number of proteins have been shown to be modified by specific reactive electrophiles.
More significantly, the present data show that viability in D. melanogaster is also sensitive to the amount of heterochromatin and that this sensitivity can be modified by specific mutations such as Su var)2-1.
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Further, we will examine whether the effects of early intensified physical exercise is modified by specific variants.
Indeed, glial ensheathing of neurons is modified by specific hormones, thus determining the availability of neuronal membrane space for synaptic inputs, with the loss of this plasticity possibly being involved in pathological processes.
Finally, studies on gene-environment interactions have found that the impact of colorectal cancer risk factors, such as smoking, BMI, and vitamin D, is modified by specific genotypes [ 37- 40].
Sick-listed employees with low back pain had similar return to work (RTW) rates at one-year follow-up in a randomized trial comparing two interventions, but the effects were modified by specific workplace related factors.
CS chains are modified by specific sulfotransferases, which catalyze the transfer of a sulfate group from 3′-phosphoadenosine 5′-phosphosulfate to C-2 of GlcUA and C-4 and/or C-6 of GalNAc.
Shared evolutionary histories appear to be modified by lineage-specific expansions or deletions.
However, we anticipate that our strategy could be modified by engineering-specific-targeted double-strand breaks (for example, by incorporating a SceI endonuclease sequence in the targeting cassette or using CRISPR-Cas9) to attempt to control the initiation of the amplification event.
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