In experiments where the Wnt signaling pathway was modified by administration of GSK3 β inhibitors or overexpression of Wnt5a, long-term repopulation was increased in mice transplanted with murine or human HSCs, but in vitro proliferation went unchanged [ 109, 110].
One potential mechanism for adverse outcomes that could be modified by the administration of colloids is the unique pathophysiology associated with hip and knee arthroplasties.
However, pronounced LPR elevations may occur in the absence of ischemia [ 28] and may not be modified by the administration of RBCs [ 29].
Several genes whose expression was modified by tungstate administration to diabetic animals may be responsible for the recovery of pancreatic function.
The effect of dehorning on lying behavior was modified by meloxicam administration, as evidenced by the significant (p< 0.01) interaction between time relative to dehorning (pre vs. post) and treatment group (meloxicam vs. control).
To confirm the fidelity of the nitric oxide readout of TNBS-induced inflammation, nitric oxide production was assessed in TNBS-exposed larvae in which inflammation had been modified by the administration of antibiotics and anti-inflammatory drugs (Oehlers et al., 2011a).
After induction of anesthesia (T0), afterload was modified by incremental administrations of nicardipine (T1-4).
Mr. Putin continues to express suspicions that the American missile-defense system in Europe is targeted at Russia, even after it was modified by the Obama administration.
But of the nearly 121,000 troubled loans that have been modified by large banks and thrifts under the administration's Home Affordable Modification Program through March, just 120 of them involved a cut in principal, according to the report by the Office of the Comptroller of the Currency and Office of Thrift Supervision.
